Quantifying the Role of Epigenetic Factors in Neurocognitive Outcomes: A Twin Study

Grant number: 1146333 | Funding period: 2018 - 2023

Completed

Abstract

We aim to identify the environmental factors in early life that contribute towards an individual brain development using MRI brain scans and related psychological skills measured in late childhood. We are using twins to better understand differences in their early life environments independent of genetics.

Related publications (3)

Direction-aware functional class scoring enrichment analysis of infinium DNA methylation data

M Ziemann, M Abeysooriya, A Bora, S Lamon, MS Kasu, MW Norris, YT Wong, JM Craig

2024-01-01

Infinium Methylation BeadChip arrays remain one of the most popular platforms for epigenome-wide association studies, but tools fo..

Genetic and environmental causes of variation in epigenetic aging across the lifespan

S Li, TL Nguyen, EM Wong, PA Dugué, GS Dite, NJ Armstrong, JM Craig, KA Mather, PS Sachdev, R Saffery, J Sung, Q Tan, A Thalamuthu, RL Milne, GG Giles, MC Southey, JL Hopper

2020-12-01

Background: DNA methylation-based biological age (DNAm age) is an important biomarker for adult health. Studies in specific age ra..

Epigenetic Influences on Neurodevelopment at 11 Years of Age: Protocol for the Longitudinal Peri/Postnatal Epigenetic Twins Study at 11 Years of Age (PETS@11)

P Leong, YJ Loke, R Saffery, T Silk, A Burnett, E Josev, K Scurrah, C Theda, A Czajko, EPK Pua, ML Seal, JM Craig

2019-12-01

Neurodevelopment is sensitive to genetic and pre/postnatal environmental influences. These effects are likely mediated by epigenet..

University of Melbourne Researchers

Katrina Scurrah